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  • Often no symptoms in early stages, possibly increasing upper abdominal pain
  • Possibly yellowing of the skin without occurrence of pain
  • Possibly new onset diabetes mellitus
  • Possibly thrombosis and inflammation of superficial veins
  • Possibly nausea and vomiting, weight loss, fever, night sweats


Risk factors
  • Frequent occurrence without presence of risk factors (origin unclear)
  • Smoking
  • Chronic pancreatitis
  • Long-standing diabetes mellitus
  • Genetic predisposition